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Distribution of antibiotic resistance genes and their association with bacteria and viruses in decentralizedsewage treatment facilities

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 3, doi: 10.1007/s11783-021-1469-4

Abstract:

• Distribution of ARGs in decentralized sewage facilities were investigated.

Keywords: Decentralized sewage treatment facilities     Antibiotic resistance genes     Virus     Metagenomics     Network    

Impacts of advanced treatment processes on elimination of antibiotic resistance genes in a municipalwastewater treatment plant

Lian Yang, Qinxue Wen, Zhiqiang Chen, Ran Duan, Pan Yang

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 3, doi: 10.1007/s11783-019-1116-5

Abstract:

The distributions of ARGs were monitored in a WWTP in Harbin during six months.

CASS had the best removal efficacy of ARGs compared to other processes in the WWTP.

UV disinfection could effectively control the HGT.

AGAC significantly remove ARGs and organics due to its high absorption capacity.

Combination of ozone and AGAC significantly improve removal of ARGs and organics.

Keywords: Antibiotic resistance genes (ARGs)     Wastewater treatment plant (WWTP)     Ultraviolet (UV)     Ozonation     Granular    

Assessment of antibiotic resistance genes in dialysis water treatment processes

Xuan Zhu, Chengsong Ye, Yuxin Wang, Lihua Chen, Lin Feng

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 3, doi: 10.1007/s11783-019-1136-1

Abstract: /p>

• Totally 35 ARGs were found in the dialysis treatment

• The effluent was associated with health risks even after RO treatment

Keywords: Dialysis water     Treatment process     Antibiotic resistance gene     High-throughput quantitative PCR     Horizontal    

Mitigating microbiological risks of potential pathogens carrying antibiotic resistance genes and virulencefactors in receiving rivers: Benefits of wastewater treatment plant upgrade

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 7, doi: 10.1007/s11783-023-1682-4

Abstract:

● Abundance of MAGs carrying ARG-VF pairs unchanged in rivers after WWTP upgrade.

Keywords: Wastewater treatment plant upgrade     Antibiotic resistance genes (ARGs)     Virulence factors (VFs)     Gene    

Elimination of antibiotic resistance genes and control of horizontal transfer risk by UV-based treatment

Virender K. Sharma, Xin Yu, Thomas J. McDonald, Chetan Jinadatha, Dionysios D. Dionysiou, Mingbao Feng

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 3, doi: 10.1007/s11783-019-1122-7

Abstract:

Antibiotic-resistant bacteria and antibiotic resistance genes are

Keywords: Antibiotic resistance bacteria     Advanced oxidation processes     Disinfection     Reactive chlorine species     Sulfate    

Complex interplay between tumor microenvironment and cancer therapy

Minhong Shen, Yibin Kang

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 426-439 doi: 10.1007/s11684-018-0663-7

Abstract: A growing body of evidence suggests that TME also plays pivotal roles in cancer treatment responses.significantly remodeled upon cancer therapies, and such change either enhances the responses or induces drug resistanceGiven the importance of TME in tumor progression and therapy resistance, strategies that remodel TME

Keywords: tumor microenvironment     therapy response     treatment resistance    

Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like

Douglas D. Fang, Joan Cao, Jitesh P. Jani, Konstantinos Tsaparikos, Alessandra Blasina, Jill Kornmann, Maruja E. Lira, Jianying Wang, Zuzana Jirout, Justin Bingham, Zhou Zhu, Yin Gu, Gerrit Los, Zdenek Hostomsky, Todd VanArsdale

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 462-476 doi: 10.1007/s11684-013-0270-6

Abstract: However, the CSC-like cells exhibited resistance to gemcitabine-induced apoptosis.spheroid-forming CSC-like cells may serve as a model system for understanding the mechanism underlying the drug resistance

Keywords: drug resistance     cancer stem cell     checkpoint kinase 1 (CHK1)     PF-00477736     lung cancer     tumorigenicity    

Presence, dissemination and removal of antibiotic resistant bacteria and antibiotic resistance genes

Qiaowen Tan, Weiying Li, Junpeng Zhang, Wei Zhou, Jiping Chen, Yue Li, Jie Ma

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 3, doi: 10.1007/s11783-019-1120-9

Abstract:

Reviewed the change of ARGs and ARB in full-scale urban drinking water systems.

Conventional processes are more promising than BAC process in ARGs removal.

Mechanisms of ARGs enrichment and spread in BAC filter and DWDSs are discussed.

Raise the need of future research on ARGs and ARB change in building plumbing systems.

Keywords: Antibiotic resistant bacteria     Antibiotic resistance genes     Water source     Drinking water treatment plant    

Prevalence of antifolate drug resistance markers in in China

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 83-92 doi: 10.1007/s11684-021-0894-x

Abstract: dhfr) and dihydropteroate synthetase (dhps) genes of Plasmodium vivax and antifolate resistance-associatedgenes were used for drug resistance surveillance.This study indicated that the antifolate resistance levels of P. vivax parasites were differentacross China and molecular markers could be used to rapidly monitor drug resistance.Results provided evidence for updating national drug policy and treatment guidelines.

Keywords: drug resistance     antifolates     molecular markers     Plasmodium vivax     China    

Biofiltration and disinfection codetermine the bacterial antibiotic resistome in drinking water: A review and meta-analysis

Kun Wan, Wenfang Lin, Shuai Zhu, Shenghua Zhang, Xin Yu

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 1, doi: 10.1007/s11783-019-1189-1

Abstract: Published data was used to analyze the fate of ARGs in water treatment.We extracted the antibiotic resistance gene (ARG) data from recent publications and analyzed ARG profilesThe absolute abundance of ARG was found to decrease with water treatment processes and was positivelyAmong treatment processes, biofiltration and chlorination were discovered to play important roles inFinally, we proposed the BAR health risks caused by biofiltration and chlorination in water treatment

Keywords: Drinking water treatment     Antibiotic resistance gene     Biofiltration     Chlorination    

Metagenomic analysis on resistance genes in water and microplastics from a mariculture system

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 1,   Pages 4-4 doi: 10.1007/s11783-021-1438-y

Abstract: Mariculture systems have been observed to host microplastics and antibiotic resistance genes (ARGs).However, more information on proliferation of ARGs and metal resistance genes (MRGs) in mariculture system

Keywords: Antibiotic resistance genes     Metal resistance genes     Metagenomic analysis     Microplastics     Mariculture    

Taking advantage of drug resistance, a new approach in the war on cancer

Liqin Wang, Rene Bernards

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 490-495 doi: 10.1007/s11684-018-0647-7

Abstract: While most cancer therapies are given in combinations that are designed to avoid drug resistance, wetherapeutic approaches that take advantage of the changes in cancer cells that arise upon development of drug resistanceThis approach is based on notion that drug resistance comes at a fitness cost to the cancer cell that

Keywords: cancer     drug resistance     genetic screens     senescence     targeted therapy    

Targeting apoptosis to manage acquired resistance to third generation EGFR inhibitors

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 701-713 doi: 10.1007/s11684-022-0951-0

Abstract: A significant clinical challenge in lung cancer treatment is management of the inevitable acquired resistancetyrosine kinase inhibitors (EGFR-TKIs), such as osimertinib, which have shown remarkable success in the treatmentof advanced NSCLC with EGFR activating mutations, in order to achieve maximal response duration or treatmentApoptosis is a major type of programmed cell death tightly associated with cancer development and treatmentaccordingly a key mechanism of drug acquired resistance in cancer therapy.

Keywords: acquired resistance     EGFR inhibitor     apoptosis     lung cancer    

Transmission of antibiotic resistance genes in agroecosystems: an overview

Jizheng HE, Zhenzhen YAN, Qinglin CHEN

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 3,   Pages 329-332 doi: 10.15302/J-FASE-2020333

Abstract: antibiotics into the environment, which imposes high selection pressure on bacteria to develop antibiotic resistanceThe spread and aggregation of antibiotic resistance genes (ARGs) in multidrug-resistant pathogens isThe future need to control and mitigate the spread of antibiotic resistance in agricultural ecosystems

Keywords: agroecosystem     antibiotic resistance     public health     soil-plant system    

swine manure with sulfamethoxazole and norfloxacin: Dynamics of microbial communities and evolution of resistance

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 5, doi: 10.1007/s11783-020-1342-x

Abstract:

• SMX addition had negative effect on acetoclastic methanogens in mesophilic AD.

Keywords: Pig manure     Antibiotics     Anaerobic digestion     Resistance genes     Microbial community    

Title Author Date Type Operation

Distribution of antibiotic resistance genes and their association with bacteria and viruses in decentralizedsewage treatment facilities

Journal Article

Impacts of advanced treatment processes on elimination of antibiotic resistance genes in a municipalwastewater treatment plant

Lian Yang, Qinxue Wen, Zhiqiang Chen, Ran Duan, Pan Yang

Journal Article

Assessment of antibiotic resistance genes in dialysis water treatment processes

Xuan Zhu, Chengsong Ye, Yuxin Wang, Lihua Chen, Lin Feng

Journal Article

Mitigating microbiological risks of potential pathogens carrying antibiotic resistance genes and virulencefactors in receiving rivers: Benefits of wastewater treatment plant upgrade

Journal Article

Elimination of antibiotic resistance genes and control of horizontal transfer risk by UV-based treatment

Virender K. Sharma, Xin Yu, Thomas J. McDonald, Chetan Jinadatha, Dionysios D. Dionysiou, Mingbao Feng

Journal Article

Complex interplay between tumor microenvironment and cancer therapy

Minhong Shen, Yibin Kang

Journal Article

Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like

Douglas D. Fang, Joan Cao, Jitesh P. Jani, Konstantinos Tsaparikos, Alessandra Blasina, Jill Kornmann, Maruja E. Lira, Jianying Wang, Zuzana Jirout, Justin Bingham, Zhou Zhu, Yin Gu, Gerrit Los, Zdenek Hostomsky, Todd VanArsdale

Journal Article

Presence, dissemination and removal of antibiotic resistant bacteria and antibiotic resistance genes

Qiaowen Tan, Weiying Li, Junpeng Zhang, Wei Zhou, Jiping Chen, Yue Li, Jie Ma

Journal Article

Prevalence of antifolate drug resistance markers in in China

Journal Article

Biofiltration and disinfection codetermine the bacterial antibiotic resistome in drinking water: A review and meta-analysis

Kun Wan, Wenfang Lin, Shuai Zhu, Shenghua Zhang, Xin Yu

Journal Article

Metagenomic analysis on resistance genes in water and microplastics from a mariculture system

Journal Article

Taking advantage of drug resistance, a new approach in the war on cancer

Liqin Wang, Rene Bernards

Journal Article

Targeting apoptosis to manage acquired resistance to third generation EGFR inhibitors

Journal Article

Transmission of antibiotic resistance genes in agroecosystems: an overview

Jizheng HE, Zhenzhen YAN, Qinglin CHEN

Journal Article

swine manure with sulfamethoxazole and norfloxacin: Dynamics of microbial communities and evolution of resistance

Journal Article